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Itrakonazol, ketokonazol i u manjoj meri flukonazol i vorikonazol su snažni inhibitori izoenzima CYP3A4 citohroma P450 i mogu povećati koncentraciju benzodiazepina u plazmi.Certain medicines really should not be utilized at or across the time of feeding on food stuff or having specified kinds of food stuff considering that interactions might aris